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hgp100(25-33)

This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal melanocytes. This peptide was used as an immunogen in multiple cancer immunotherapy studies.
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Overview
Description This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal melanocytes. This peptide was used as an immunogen in multiple cancer immunotherapy studies.
Sequence
{Lys}{Val}{Pro}{Arg}{Asn}{Gln}{Asp}{Trp}{Leu}
Sequence Shortening KVPRNQDWL
Molecular Weight 1155.3
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Properties
Purity > 95%
Solubility Soluble in Ultrapure water under 1mg/ml
Form Lyophilized
Storage Store at -20°C.
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Citations
Qi Tang, et al. Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin. Nat Commun. (2023-11)
Minute L, et al. Cellular cytotoxicity is a form of immunogenic cell death. Journal for ImmunoTherapy of Cancer. (2020-03)
, et al. Correction: Cellular cytotoxicity is a form of immunogenic cell death. J Immunother Cancer. (2020)
Etxeberria I, et al. Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells. Cancer Cell. (2019-12)
Chatterjee Shilpak, et al. CD38-NADAxis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. (2018)